Education:
MD, Northwestern University Medical School, Chicago, IL; BS, Northwestern University Medical Sciences, Chicago, IL

Molecular Mechanisms of Liver Transplant Ischemia/Reperfusion Injury

Transcriptional regulation of the human iNOS gene; Molecular mechanisms of liver injury; Liver transplant ischemia/reperfusion injury; Gene therapy for liver cancer; HCC signaling pathways; Liver cancer therapy

Recent Publications:

Steel JL, George CJ, Terhorst L, Yabes JG, Reyes V, Zandberg DP, Nilsen M, Kiefer G, Johnson J, Marsh C, Bierenbaum J, Tageja N, Krauze M, VanderWeele R, Goel G, Ramineni G, Antoni M, Vodovotz Y, Walker J, Tohme S, Billiar T, Geller DA. Patient, family caregiver, and economic outcomes of an integrated screening and novel stepped collaborative care intervention in the oncology setting in the USA (CARES): a randomised, parallel, phase 3 trial. Lancet. 2024; 403:1351-1361.

Kaltenmeier C, Geller DA, Ganesh S, Tohme S, Molinari M, Tevar A, Hughes C, Humar A. Living Donor Liver Transplantation for Colorectal Cancer Liver Metastases (CRLM): midterm outcomes at a single center in North America.  Am J Transplant. 2024 ;24:681-687.

Yu YP, Liu S, Geller D, Luo JH. Serum fusion transcripts to assess the risk of hepatocellular carcinoma and the impact of cancer treatment through machine learning.  Am J Pathol. 2024 Mar 25:  Online ahead of print.

Wu Q, Li X, Yang Y, Huang J, Yao M, Li J, Huang Y, Cai X, Geller DA, Yan Y. MICA+ Tumor Cell Upregulated Macrophage-Secreted MMP9 via PROS1-AXL Axis to Induce Tumor Immune Escape in Advanced Hepatocellular Carcinoma (HCC).  Cancers (Basel). 2024 Jan 8; Online ahead of print

Du Q, Liu S, Dong K, Cui X, Luo J, Geller DA. Downregulation of iNOS/NO promotes epithelial-mesenchymal transition and metastasis in colorectal cancer. Mol Cancer Res. 2023; 21:102-114.

Dogeas E, Geller DA, Tohme S, Steel J, Lo W, Morocco B, Tevar A, Molinari M, Hughes C, Humar A. Textbook Outcomes following Open Live Donor Right Hepatectomy and Open Right Hepatic Lobectomy for Cancer in 686 patients: Re-defining the Benchmark.  Ann Surg. 2023;  278:e256-e263

Behari J, Gougol A, Wang R, Luu HN, Paragomi P, Yu YC, Molinari M, Chopra K, Malik SM, Geller D, Yuan JM. Incidence of hepatocellular carcinoma in nonalcoholic fatty liver disease without cirrhosis or advanced liver fibrosis.  Hepatol Commun. 2023 Jul 3; 7(7). Online ahead of print.

Cui X, Zhao H, Wei S, Du Q, Dong K, Yan Y, Geller DA. Hepatocellular carcinoma-derived FOXO1 inhibits tumor progression by suppressing IL-6 secretion from macrophages.  Neoplasia. 2023 Apr 12;. Online ahead of print.